Check out design3's 'Industry Insight' for more exclusive interviews:
http://www.design3.com/industry-insight

Edmund McMillen is one half of the rawest game company in the industry, Team Meat, and also well known for his own personal projects (ever heard of an addictive little game called The Binding of Isaac?). Ben Mears sits down with a fellow Santa Cruz resident to talk about everything from independent game producion, to internet hecklers, to the perks of being an animal control officer. Make sure you don't miss Edmund's invaluable tips on game design, working with publishers, and exclusive insight into Team Meat's upcoming projects.

Team Meat:
http://www.supermeatboy.com